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Amino acid–dependent stability of the acyl linkage in aminoacyl-tRNA

Aminoacyl-tRNAs are the biologically active substrates for peptide bond formation in protein synthesis. The stability of the acyl linkage in each aminoacyl-tRNA, formed through an ester bond that connects the amino acid carboxyl group with the tRNA terminal 3′-OH group, is thus important. While the...

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Detalles Bibliográficos
Autores principales: Peacock, Jacob R., Walvoord, Ryan R., Chang, Angela Y., Kozlowski, Marisa C., Gamper, Howard, Hou, Ya-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024630/
https://www.ncbi.nlm.nih.gov/pubmed/24751649
http://dx.doi.org/10.1261/rna.044123.113