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An adaptable pentaloop defines a robust neomycin-B RNA aptamer with conditional ligand-bound structures

Aptamers can be highly specific for their targets, which implies precise molecular recognition between aptamer and target. However, as small polymers, their structures are more subject to environmental conditions than the more constrained longer RNAs such as those that constitute the ribosome. To un...

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Detalles Bibliográficos
Autores principales: Ilgu, Muslum, Fulton, D. Bruce, Yennamalli, Ragothaman M., Lamm, Monica H., Sen, Taner Z., Nilsen-Hamilton, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024636/
https://www.ncbi.nlm.nih.gov/pubmed/24757168
http://dx.doi.org/10.1261/rna.041145.113