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An adaptable pentaloop defines a robust neomycin-B RNA aptamer with conditional ligand-bound structures
Aptamers can be highly specific for their targets, which implies precise molecular recognition between aptamer and target. However, as small polymers, their structures are more subject to environmental conditions than the more constrained longer RNAs such as those that constitute the ribosome. To un...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024636/ https://www.ncbi.nlm.nih.gov/pubmed/24757168 http://dx.doi.org/10.1261/rna.041145.113 |