Characterization of age‐associated alterations of islet function and structure in diabetic mutant cryptochrome 1 transgenic mice

AIMS/INTRODUCTION: In earlier reports, we described that transgenic (Tg) mice ubiquitously expressing cryptochrome1 (CRY1) with a mutation in cysteine414 (CRY1‐AP Tg mice) show an early‐onset insulin‐secretory defect of diabetes mellitus resembling human maturity‐onset diabetes of the young (MODY)....

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Detalles Bibliográficos
Autores principales: Okano, Satoshi, Hayasaka, Kiyoshi, Igarashi, Masahiko, Togashi, Yoshiyuki, Nakajima, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-Blackwell 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025103/
https://www.ncbi.nlm.nih.gov/pubmed/24843691
http://dx.doi.org/10.1111/jdi.12080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025103/
https://www.ncbi.nlm.nih.gov/pubmed/24843691
http://dx.doi.org/10.1111/jdi.12080

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