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Characterization of age‐associated alterations of islet function and structure in diabetic mutant cryptochrome 1 transgenic mice
AIMS/INTRODUCTION: In earlier reports, we described that transgenic (Tg) mice ubiquitously expressing cryptochrome1 (CRY1) with a mutation in cysteine414 (CRY1‐AP Tg mice) show an early‐onset insulin‐secretory defect of diabetes mellitus resembling human maturity‐onset diabetes of the young (MODY)....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wiley-Blackwell
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025103/ https://www.ncbi.nlm.nih.gov/pubmed/24843691 http://dx.doi.org/10.1111/jdi.12080 |