Protective role of human insulin against the cytotoxicity associated with human mutant S20G islet amyloid polypeptide

AIMS/INTRODUCTION: Islet amyloid polypeptide (IAPP) is a main component of islet amyloid in type 2 diabetes and cosecreted from β‐cell with insulin. Clinical evidence from the patients with S20G mutation of the IAPP gene, as well as experimental evidence that insulin could inhibit amyloid formation...

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Detalles Bibliográficos
Autores principales: Morita, Shuhei, Ueyama, Minoru, Sakagashira, Setsuya, Shimajiri, Yoshinori, Yamana, Akiko, Furuta, Machi, Sanke, Tokio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-Blackwell 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025108/
https://www.ncbi.nlm.nih.gov/pubmed/24843692
http://dx.doi.org/10.1111/jdi.12069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025108/
https://www.ncbi.nlm.nih.gov/pubmed/24843692
http://dx.doi.org/10.1111/jdi.12069

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