YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells

BACKGROUND: Sox2, a transcription factor and an embryonic stem cell marker, has been implicated in the pathogenesis of breast cancer (BC). YB-1 is another transcription factor that has been shown to promote stemness in BC cells. METHODS: Western blotting, quantitative PCR, and siRNAs were used to qu...

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Detalles Bibliográficos
Autores principales: Jung, Karen, Wu, Fang, Wang, Peng, Ye, Xiaoxia, Abdulkarim, Bassam S, Lai, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025193/
https://www.ncbi.nlm.nih.gov/pubmed/24885403
http://dx.doi.org/10.1186/1471-2407-14-328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025193/
https://www.ncbi.nlm.nih.gov/pubmed/24885403
http://dx.doi.org/10.1186/1471-2407-14-328

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