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HIV-1 Quasispecies Delineation by Tag Linkage Deep Sequencing
Trade-offs between throughput, read length, and error rates in high-throughput sequencing limit certain applications such as monitoring viral quasispecies. Here, we describe a molecular-based tag linkage method that allows assemblage of short sequence reads into long DNA fragments. It enables haplot...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026136/ https://www.ncbi.nlm.nih.gov/pubmed/24842159 http://dx.doi.org/10.1371/journal.pone.0097505 |