HIV-1 Quasispecies Delineation by Tag Linkage Deep Sequencing

Trade-offs between throughput, read length, and error rates in high-throughput sequencing limit certain applications such as monitoring viral quasispecies. Here, we describe a molecular-based tag linkage method that allows assemblage of short sequence reads into long DNA fragments. It enables haplot...

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Detalles Bibliográficos
Autores principales: Wu, Nicholas C., De La Cruz, Justin, Al-Mawsawi, Laith Q., Olson, C. Anders, Qi, Hangfei, Luan, Harding H., Nguyen, Nguyen, Du, Yushen, Le, Shuai, Wu, Ting-Ting, Li, Xinmin, Lewis, Martha J., Yang, Otto O., Sun, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026136/
https://www.ncbi.nlm.nih.gov/pubmed/24842159
http://dx.doi.org/10.1371/journal.pone.0097505

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