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The Injectable-Only Contraceptive Medroxyprogesterone Acetate, Unlike Norethisterone Acetate and Progesterone, Regulates Inflammatory Genes in Endocervical Cells via the Glucocorticoid Receptor

Clinical studies suggest that the injectable contraceptive medroxyprogesterone acetate (MPA) increases susceptibility to infections such as HIV-1, unlike the injectable contraceptive norethisterone enanthate (NET-EN). We investigated the differential effects, molecular mechanism of action and steroi...

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Detalles Bibliográficos
Autores principales: Govender, Yashini, Avenant, Chanel, Verhoog, Nicolette J. D., Ray, Roslyn M., Grantham, Nicholas J., Africander, Donita, Hapgood, Janet P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026143/
https://www.ncbi.nlm.nih.gov/pubmed/24840644
http://dx.doi.org/10.1371/journal.pone.0096497