X-ray Structures of Human Furin in Complex with Competitive Inhibitors

[Image: see text] Furin inhibitors are promising therapeutics for the treatment of cancer and numerous infections caused by bacteria and viruses, including the highly lethal Bacillus anthracis or the pandemic influenza virus. Development and improvement of inhibitors for pharmacological use require...

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Detalles Bibliográficos
Autores principales: Dahms, Sven O., Hardes, Kornelia, Becker, Gero L., Steinmetzer, Torsten, Brandstetter, Hans, Than, Manuel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026159/
https://www.ncbi.nlm.nih.gov/pubmed/24666235
http://dx.doi.org/10.1021/cb500087x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026159/
https://www.ncbi.nlm.nih.gov/pubmed/24666235
http://dx.doi.org/10.1021/cb500087x

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