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X-ray Structures of Human Furin in Complex with Competitive Inhibitors
[Image: see text] Furin inhibitors are promising therapeutics for the treatment of cancer and numerous infections caused by bacteria and viruses, including the highly lethal Bacillus anthracis or the pandemic influenza virus. Development and improvement of inhibitors for pharmacological use require...
Autores principales: | Dahms, Sven O., Hardes, Kornelia, Becker, Gero L., Steinmetzer, Torsten, Brandstetter, Hans, Than, Manuel E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026159/ https://www.ncbi.nlm.nih.gov/pubmed/24666235 http://dx.doi.org/10.1021/cb500087x |
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