Changes in Gene Expression Associated with FTO Overexpression in Mice

Single nucleotide polymorphisms in the first intron of the fat-mass-and-obesity-related gene FTO are associated with increased body weight and adiposity. Increased expression of FTO is likely underlying this obesity phenotype, as mice with two additional copies of Fto (FTO-4 mice) exhibit increased...

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Detalles Bibliográficos
Autores principales: Merkestein, Myrte, McTaggart, James S., Lee, Sheena, Kramer, Holger B., McMurray, Fiona, Lafond, Mathilde, Boutens, Lily, Cox, Roger, Ashcroft, Frances M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026227/
https://www.ncbi.nlm.nih.gov/pubmed/24842286
http://dx.doi.org/10.1371/journal.pone.0097162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026227/
https://www.ncbi.nlm.nih.gov/pubmed/24842286
http://dx.doi.org/10.1371/journal.pone.0097162

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