P-glycoprotein- and organic anion-transporting polypeptide-mediated transport of periplocin may lead to drug–herb/drug–drug interactions

Periplocin, an active and toxic component of the traditional Chinese herbal medicine Periploca sepium Bge, is a cardiac glycoside compound that has been implicated in various clinical accidents. This study investigated the role of transporters in the intestinal absorption and biliary excretion of pe...

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Detalles Bibliográficos
Autores principales: Liang, Sheng, Deng, Fengchun, Xing, Haiyan, Wen, He, Shi, Xiaoyan, Martey, Orleans Nii, Koomson, Emmanuel, He, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026310/
https://www.ncbi.nlm.nih.gov/pubmed/24872678
http://dx.doi.org/10.2147/DDDT.S61024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026310/
https://www.ncbi.nlm.nih.gov/pubmed/24872678
http://dx.doi.org/10.2147/DDDT.S61024

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