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Ribosomal Proteins L5 and L11 Cooperatively Inactivate c-Myc via RNA-induced Silencing Complex

Oncogene MYC is highly expressed in many human cancers and functions as a global regulator of ribosome biogenesis. Previously, we reported that ribosomal protein (RP) L11 binds to c-Myc and inhibits its transcriptional activity in response to ribosomal stress. Here, we show that another ribosomal pr...

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Detalles Bibliográficos
Autores principales: Liao, Jun-Ming, Zhou, Xiang, Gatignol, Anne, Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026346/
https://www.ncbi.nlm.nih.gov/pubmed/24141778
http://dx.doi.org/10.1038/onc.2013.430