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Oral Vaccination with Heat Inactivated Mycobacterium bovis Activates the Complement System to Protect against Tuberculosis

Tuberculosis (TB) remains a pandemic affecting billions of people worldwide, thus stressing the need for new vaccines. Defining the correlates of vaccine protection is essential to achieve this goal. In this study, we used the wild boar model for mycobacterial infection and TB to characterize the pr...

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Detalles Bibliográficos
Autores principales: Beltrán-Beck, Beatriz, de la Fuente, José, Garrido, Joseba M., Aranaz, Alicia, Sevilla, Iker, Villar, Margarita, Boadella, Mariana, Galindo, Ruth C., Pérez de la Lastra, José M., Moreno-Cid, Juan A., Fernández de Mera, Isabel G., Alberdi, Pilar, Santos, Gracia, Ballesteros, Cristina, Lyashchenko, Konstantin P., Minguijón, Esmeralda, Romero, Beatriz, de Juan, Lucía, Domínguez, Lucas, Juste, Ramón, Gortazar, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026474/
https://www.ncbi.nlm.nih.gov/pubmed/24842853
http://dx.doi.org/10.1371/journal.pone.0098048