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Human Sarcoma Growth Is Sensitive to Small-Molecule Mediated AXIN Stabilization

Sarcomas are mesenchymal tumors showing high molecular heterogeneity, reflected at the histological level by the existence of more than fifty different subtypes. Genetic and epigenetic evidences link aberrant activation of the Wnt signaling to growth and progression of human sarcomas. This phenomeno...

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Detalles Bibliográficos
Autores principales: De Robertis, Alessandra, Mennillo, Federica, Rossi, Marco, Valensin, Silvia, Tunici, Patrizia, Mori, Elisa, Caradonna, Nicola, Varrone, Maurizio, Salerno, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026528/
https://www.ncbi.nlm.nih.gov/pubmed/24842792
http://dx.doi.org/10.1371/journal.pone.0097847