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Influence of ARHGEF3 and RHOA Knockdown on ACTA2 and Other Genes in Osteoblasts and Osteoclasts

Osteoporosis is a common bone disease that has a strong genetic component. Genome-wide linkage studies have identified the chromosomal region 3p14-p22 as a quantitative trait locus for bone mineral density (BMD). We have previously identified associations between variation in two related genes locat...

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Detalles Bibliográficos
Autores principales: Mullin, Benjamin H., Mamotte, Cyril, Prince, Richard L., Wilson, Scott G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026532/
https://www.ncbi.nlm.nih.gov/pubmed/24840563
http://dx.doi.org/10.1371/journal.pone.0098116