Self-assembled micelles of novel amphiphilic copolymer cholesterol-coupled F68 containing cabazitaxel as a drug delivery system

Despite being one of the most promising amphiphilic block copolymers, use of Pluronic F68 in drug delivery is limited due to its high critical micelle concentration (CMC). In this study, we developed a novel F68 derivative, cholesterol-coupled F68 (F68-CHMC). This new derivative has a CMC of 10 μg/m...

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Detalles Bibliográficos
Autores principales: Song, Yanzhi, Tian, Qingjing, Huang, Zhenjun, Fan, Di, She, Zhennan, Liu, Xinrong, Cheng, Xiaobo, Yu, Bin, Deng, Yihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026555/
https://www.ncbi.nlm.nih.gov/pubmed/24872693
http://dx.doi.org/10.2147/IJN.S61220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026555/
https://www.ncbi.nlm.nih.gov/pubmed/24872693
http://dx.doi.org/10.2147/IJN.S61220

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