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Generation of Individual Diversity: A Too Neglected Fundamental Property of Adaptive Immune System
The fitness gains resulting from development of the adaptive immune system (AIS) during evolution are still the subject of hot debate. A large random repertoire of antigenic receptors is costly to develop and could be the source of autoimmune reactions. And yet, despite their drawbacks, AIS-like sys...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026687/ https://www.ncbi.nlm.nih.gov/pubmed/24860570 http://dx.doi.org/10.3389/fimmu.2014.00208 |