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Protein phosphorylation in neurodegeneration: friend or foe?

Protein misfolding and aggregation is a common hallmark in neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), and fronto-temporal dementia (FTD). In these disorders, the misfolding and aggregation of specific proteins occurs alongside neuronal degene...

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Detalles Bibliográficos
Autores principales: Tenreiro, Sandra, Eckermann, Katrin, Outeiro, Tiago F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026737/
https://www.ncbi.nlm.nih.gov/pubmed/24860424
http://dx.doi.org/10.3389/fnmol.2014.00042