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Expression of heparanase in soft tissue sarcomas of adults

BACKGROUND: Heparanase is an endo-β-D-glucuronidase that cleaves heparan sulfate chains of proteoglycans, resulting in the disassembly of the extracellular matrix. Heparanase has a central role in the development of various tumors, and its expression has been associated with increased tumor growth,...

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Detalles Bibliográficos
Autores principales: Kazarin, Olga, Ilan, Neta, Naroditzky, Inna, Ben-Itzhak, Ofer, Vlodavsky, Israel, Bar-Sela, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026817/
https://www.ncbi.nlm.nih.gov/pubmed/24887057
http://dx.doi.org/10.1186/1756-9966-33-39