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Type three secretion system-mediated escape of Burkholderia pseudomallei into the host cytosol is critical for the activation of NFκB

BACKGROUND: Burkholderia pseudomallei is the causative agent of melioidosis, a potentially fatal disease endemic in Southeast Asia and Northern Australia. This Gram-negative pathogen possesses numerous virulence factors including three “injection type” type three secretion systems (T3SSs). B. pseudo...

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Detalles Bibliográficos
Autores principales: Teh, Boon Eng, French, Christopher Todd, Chen, Yahua, Chen, Isabelle Gek Joo, Wu, Ting-Hsiang, Sagullo, Enrico, Chiou, Pei-Yu, Teitell, Michael A, Miller, Jeff F, Gan, Yunn-Hwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026835/
https://www.ncbi.nlm.nih.gov/pubmed/24884837
http://dx.doi.org/10.1186/1471-2180-14-115