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Pathway-Driven Discovery of Rare Mutational Impact on Cancer

Identifying driver mutation is important in understanding disease mechanism and future application of custom tailored therapeutic decision. Functional analysis of mutational impact usually focuses on the gene expression level of the mutated gene itself. However, complex regulatory network may cause...

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Detalles Bibliográficos
Autores principales: Ahn, TaeJin, Park, Taesung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026869/
https://www.ncbi.nlm.nih.gov/pubmed/24883302
http://dx.doi.org/10.1155/2014/171892