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Pathway-Driven Discovery of Rare Mutational Impact on Cancer
Identifying driver mutation is important in understanding disease mechanism and future application of custom tailored therapeutic decision. Functional analysis of mutational impact usually focuses on the gene expression level of the mutated gene itself. However, complex regulatory network may cause...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026869/ https://www.ncbi.nlm.nih.gov/pubmed/24883302 http://dx.doi.org/10.1155/2014/171892 |