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Follistatin, an Activin Antagonist, Ameliorates Renal Interstitial Fibrosis in a Rat Model of Unilateral Ureteral Obstruction

Activin, a member of the TGF-β superfamily, regulates cell growth and differentiation in various cell types. Activin A acts as a negative regulator of renal development as well as tubular regeneration after renal injury. However, it remains unknown whether activin A is involved in renal fibrosis. To...

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Detalles Bibliográficos
Autores principales: Maeshima, Akito, Mishima, Keiichiro, Yamashita, Shin, Nakasatomi, Masao, Miya, Masaaki, Sakurai, Noriyuki, Sakairi, Toru, Ikeuchi, Hidekazu, Hiromura, Keiju, Hasegawa, Yoshihisa, Kojima, Itaru, Nojima, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026945/
https://www.ncbi.nlm.nih.gov/pubmed/24883308
http://dx.doi.org/10.1155/2014/376191