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ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?

Genetic polymorphisms in ABC (ATP-binding cassette) transporter genes are associated with differential responses to chemotherapy in various cancers including pancreatic cancer. In this study, four SNPs in the ABCB1, ABCC1, and ABCG2 genes were investigated in normal and pancreatic cancerous specimen...

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Detalles Bibliográficos
Autores principales: Pang, Li, Word, Beverly, Xu, Joshua, Wang, Honggang, Hammons, George, Huang, Shiew-Mei, Lyn-Cook, Beverly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026978/
https://www.ncbi.nlm.nih.gov/pubmed/24883056
http://dx.doi.org/10.1155/2014/414931