Development of a Novel Anti-HIF-1α Screening System Coupled with Biochemical and Biological Validation for Rapidly Selecting Potent Anti-Cancer Compounds

Breast cancer (BCa) is the most diagnosed cancer and the second leading cause of cancer death in the American women. Adaptation to the hypoxic environment seen in solid tumors is critical for tumor cell survival and growth. The activation of hypoxia inducible factor-1 alpha (HIF-1α), an important ma...

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Detalles Bibliográficos
Autores principales: Lu, Yi, Madu, Chikezie, Masters, Jordan, Lu, Andrew, Li, Liyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026995/
https://www.ncbi.nlm.nih.gov/pubmed/24847382
http://dx.doi.org/10.7150/jca.9205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026995/
https://www.ncbi.nlm.nih.gov/pubmed/24847382
http://dx.doi.org/10.7150/jca.9205

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