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Regulation of Desmocollin3 Expression by Promoter Hypermethylation is Associated with Advanced Esophageal Adenocarcinomas

BACKGROUND: Desmocollin3 (DSC3) is a member of the cadherin superfamily of calcium-dependent cell adhesion molecules and plays an important role in tumor invasion and metastasis. In this study, we investigated the epigenetic mechanism that regulates DSC3 expression in esophageal adenocarcinomas (EAC...

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Detalles Bibliográficos
Autores principales: Wang, Qinggang, Peng, DunFa, Zhu, Shoumin, Chen, Zheng, Hu, TianLing, Soutto, Mohammed, Saad, Rama, Zhang, Shutian, EI-Rifai, Wael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026999/
https://www.ncbi.nlm.nih.gov/pubmed/24847386
http://dx.doi.org/10.7150/jca.9145