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Anti-hnRNP B1 (RA33) Autoantibodies Are Associated with the Clinical Phenotype in Russian Patients with Rheumatoid Arthritis and Systemic Sclerosis

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are potent autoantigenic targets in systemic autoimmune rheumatic diseases (SARD). Loss of tolerance to the RA33 complex consisting of hnRNP A2 and its alternatively spliced variants B1 and B2 has been the interest of rheumatologists. A novel ELISA f...

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Detalles Bibliográficos
Autores principales: Maslyanskiy, Aleksey, Lazareva, Natalya, Olinek, Polina, Schierack, Peter, Hentschel, Christian, Cuccato, Juliane, Bogdanos, Dimitrios P., Lapin, Sergey V., Roggenbuck, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027001/
https://www.ncbi.nlm.nih.gov/pubmed/24883333
http://dx.doi.org/10.1155/2014/516593