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Opioid-Induced Constipation: Pathophysiology, Clinical Consequences, and Management
Although opioids offer potent analgesia for severe acute and chronic noncancer pain, adverse gastrointestinal effects potentially undermine their clinical utility. In particular, between 40% and 95% of patients develop opioid-induced constipation (OIC). Therefore, there is a consensus that patients...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027019/ https://www.ncbi.nlm.nih.gov/pubmed/24883055 http://dx.doi.org/10.1155/2014/141737 |