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Opioid-Induced Constipation: Pathophysiology, Clinical Consequences, and Management

Although opioids offer potent analgesia for severe acute and chronic noncancer pain, adverse gastrointestinal effects potentially undermine their clinical utility. In particular, between 40% and 95% of patients develop opioid-induced constipation (OIC). Therefore, there is a consensus that patients...

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Detalles Bibliográficos
Autores principales: Kumar, Lalit, Barker, Chris, Emmanuel, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027019/
https://www.ncbi.nlm.nih.gov/pubmed/24883055
http://dx.doi.org/10.1155/2014/141737