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Vicinal: a method for the determination of ncRNA ends using chimeric reads from RNA-seq experiments

Non-coding (nc)RNAs are important structural and regulatory molecules. Accurate determination of the primary sequence and secondary structure of ncRNAs is important for understanding their functions. During cDNA synthesis, RNA 3′ end stem-loops can self-prime reverse transcription, creating RNA–cDNA...

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Detalles Bibliográficos
Autores principales: Lu, Zhipeng, Matera, A. Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027162/
https://www.ncbi.nlm.nih.gov/pubmed/24623808
http://dx.doi.org/10.1093/nar/gku207