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SAXS analysis of the tRNA-modifying enzyme complex MnmE/MnmG reveals a novel interaction mode and GTP-induced oligomerization

Transfer ribonucleic acid (tRNA) modifications, especially at the wobble position, are crucial for proper and efficient protein translation. MnmE and MnmG form a protein complex that is implicated in the carboxymethylaminomethyl modification of wobble uridine (cmnm(5)U34) of certain tRNAs. MnmE is a...

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Detalles Bibliográficos
Autores principales: Fislage, Marcus, Brosens, Elke, Deyaert, Egon, Spilotros, Alessandro, Pardon, Els, Loris, Remy, Steyaert, Jan, Garcia-Pino, Abel, Versées, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027165/
https://www.ncbi.nlm.nih.gov/pubmed/24634441
http://dx.doi.org/10.1093/nar/gku213