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SAXS analysis of the tRNA-modifying enzyme complex MnmE/MnmG reveals a novel interaction mode and GTP-induced oligomerization
Transfer ribonucleic acid (tRNA) modifications, especially at the wobble position, are crucial for proper and efficient protein translation. MnmE and MnmG form a protein complex that is implicated in the carboxymethylaminomethyl modification of wobble uridine (cmnm(5)U34) of certain tRNAs. MnmE is a...
Autores principales: | Fislage, Marcus, Brosens, Elke, Deyaert, Egon, Spilotros, Alessandro, Pardon, Els, Loris, Remy, Steyaert, Jan, Garcia-Pino, Abel, Versées, Wim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027165/ https://www.ncbi.nlm.nih.gov/pubmed/24634441 http://dx.doi.org/10.1093/nar/gku213 |
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