Estimating telomere length from whole genome sequence data

Telomeres play a key role in replicative ageing and undergo age-dependent attrition in vivo. Here, we report a novel method, TelSeq, to measure average telomere length from whole genome or exome shotgun sequence data. In 260 leukocyte samples, we show that TelSeq results correlate with Southern blot...

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Detalles Bibliográficos
Autores principales: Ding, Zhihao, Mangino, Massimo, Aviv, Abraham, Spector, Tim, Durbin, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027178/
https://www.ncbi.nlm.nih.gov/pubmed/24609383
http://dx.doi.org/10.1093/nar/gku181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027178/
https://www.ncbi.nlm.nih.gov/pubmed/24609383
http://dx.doi.org/10.1093/nar/gku181

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