Molecular population dynamics of DNA structures in a bcl-2 promoter sequence is regulated by small molecules and the transcription factor hnRNP LL

Minute difference in free energy change of unfolding among structures in an oligonucleotide sequence can lead to a complex population equilibrium, which is rather challenging for ensemble techniques to decipher. Herein, we introduce a new method, molecular population dynamics (MPD), to describe the...

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Detalles Bibliográficos
Autores principales: Cui, Yunxi, Koirala, Deepak, Kang, HyunJin, Dhakal, Soma, Yangyuoru, Philip, Hurley, Laurence H., Mao, Hanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027204/
https://www.ncbi.nlm.nih.gov/pubmed/24609386
http://dx.doi.org/10.1093/nar/gku185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027204/
https://www.ncbi.nlm.nih.gov/pubmed/24609386
http://dx.doi.org/10.1093/nar/gku185

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