Molecular dissection of the domain architecture and catalytic activities of human PrimPol

PrimPol is a primase–polymerase involved in nuclear and mitochondrial DNA replication in eukaryotic cells. Although PrimPol is predicted to possess an archaeo-eukaryotic primase and a UL52-like zinc finger domain, the role of these domains has not been established. Here, we report that the proposed...

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Detalles Bibliográficos
Autores principales: Keen, Benjamin A., Jozwiakowski, Stanislaw K., Bailey, Laura J., Bianchi, Julie, Doherty, Aidan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027207/
https://www.ncbi.nlm.nih.gov/pubmed/24682820
http://dx.doi.org/10.1093/nar/gku214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027207/
https://www.ncbi.nlm.nih.gov/pubmed/24682820
http://dx.doi.org/10.1093/nar/gku214

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