Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA

FANCD2 and FANCI function together in the Fanconi anemia network of deoxyribonucleic acid (DNA) crosslink repair. These proteins form the dimeric ID2 complex that binds DNA and becomes monoubiquitinated upon exposure of cells to DNA crosslinking agents. The monoubiquitinated ID2 complex is thought t...

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Detalles Bibliográficos
Autores principales: Longerich, Simonne, Kwon, Youngho, Tsai, Miaw-Sheue, Hlaing, Aye Su, Kupfer, Gary M., Sung, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027212/
https://www.ncbi.nlm.nih.gov/pubmed/24623813
http://dx.doi.org/10.1093/nar/gku198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027212/
https://www.ncbi.nlm.nih.gov/pubmed/24623813
http://dx.doi.org/10.1093/nar/gku198

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