HSCARG, a novel regulator of H2A ubiquitination by downregulating PRC1 ubiquitin E3 ligase activity, is essential for cell proliferation

Histone H2A ubiquitination plays critical roles in transcriptional repression and deoxyribonucleic acid (DNA) damage response. More attention has been focused on ubiquitin E3 ligases of H2A, however, less is known about the negative regulators of H2A ubiquitination. Here we identified HSCARG as a ne...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Bin, Li, Shangze, Zhang, Xiaodong, Zheng, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027218/
https://www.ncbi.nlm.nih.gov/pubmed/24711370
http://dx.doi.org/10.1093/nar/gku230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027218/
https://www.ncbi.nlm.nih.gov/pubmed/24711370
http://dx.doi.org/10.1093/nar/gku230

Ejemplares similares