Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device

Despite the development of potent siRNAs that effectively target genes responsible for skin disorders, translation to the clinic has been hampered by inefficient delivery through the stratum corneum barrier and into the live cells of the epidermis. Although hypodermic needles can be used to transpor...

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Detalles Bibliográficos
Autores principales: Hickerson, Robyn P, Wey, Winston C, Rimm, David L, Speaker, Tycho, Suh, Susie, Flores, Manuel A, Gonzalez-Gonzalez, Emilio, Leake, Devin, Contag, Christopher H, Kaspar, Roger L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027428/
https://www.ncbi.nlm.nih.gov/pubmed/24150576
http://dx.doi.org/10.1038/mtna.2013.56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027428/
https://www.ncbi.nlm.nih.gov/pubmed/24150576
http://dx.doi.org/10.1038/mtna.2013.56

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