Expression site attenuation mechanistically links antigenic variation and development in Trypanosoma brucei

We have discovered a new mechanism of monoallelic gene expression that links antigenic variation, cell cycle, and development in the model parasite Trypanosoma brucei. African trypanosomes possess hundreds of variant surface glycoprotein (VSG) genes, but only one is expressed from a telomeric expres...

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Detalles Bibliográficos
Autores principales: Batram, Christopher, Jones, Nicola G, Janzen, Christian J, Markert, Sebastian M, Engstler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027811/
https://www.ncbi.nlm.nih.gov/pubmed/24844706
http://dx.doi.org/10.7554/eLife.02324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027811/
https://www.ncbi.nlm.nih.gov/pubmed/24844706
http://dx.doi.org/10.7554/eLife.02324

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