Pristimerin, a quinonemethide triterpenoid, induces apoptosis in pancreatic cancer cells through the inhibition of pro-survival Akt/NF-κB/mTOR signaling proteins and anti-apoptotic Bcl-2

Lack of effective therapeutics for pancreatic cancer at the present time underscores the dire need for safe and effective agents for the treatment of this malignancy. In the present study, we have evaluated the anticancer activity and the mechanism of action of pristimerin (PM), a quinonemethide tri...

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Detalles Bibliográficos
Autores principales: DEEB, DORRAH, GAO, XIAOHUA, LIU, YONG BO, PINDOLIA, KIRIT, GAUTAM, SUBHASH C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027926/
https://www.ncbi.nlm.nih.gov/pubmed/24603988
http://dx.doi.org/10.3892/ijo.2014.2325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027926/
https://www.ncbi.nlm.nih.gov/pubmed/24603988
http://dx.doi.org/10.3892/ijo.2014.2325

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