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Na(v)1.1 Modulation by a Novel Triazole Compound Attenuates Epileptic Seizures in Rodents
[Image: see text] Here, we report the discovery of a novel anticonvulsant drug with a molecular organization based on the unique scaffold of rufinamide, an anti-epileptic compound used in a clinical setting to treat severe epilepsy disorders such as Lennox-Gastaut syndrome. Although accumulating evi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027953/ https://www.ncbi.nlm.nih.gov/pubmed/24635129 http://dx.doi.org/10.1021/cb500108p |