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Dimethylarsinothioyl Glutathione as a Metabolite in Human Multiple Myeloma Cell Lines upon Exposure to Darinaparsin

[Image: see text] Here, we report the identification of dimethylarsinothioyl glutathione (DMMTA(V)(GS)) as a metabolite in cellular extracts of dimethyarsinous glutathione (Darinaparsin, DMA(III)(GS)) treated human multiple myeloma (MM) cell lines. Co-elution of sulfur and arsenic on the inductively...

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Detalles Bibliográficos
Autores principales: Yehiayan, Lucy, Stice, Szabina, Liu, Guangliang, Matulis, Shannon, Boise, Lawrence H., Cai, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027956/
https://www.ncbi.nlm.nih.gov/pubmed/24624948
http://dx.doi.org/10.1021/tx400386c