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Temporal induction of immunoregulatory processes coincides with age-dependent resistance to viral-induced Type 1 Diabetes

The dilute plasma cytokine milieu associated with Type 1 diabetes (T1D), while difficult to measure directly, is sufficient to drive transcription in a bioassay that uses healthy leukocytes as reporters. Previously, we reported disease-associated, partially IL-1 dependent, transcriptional signatures...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Guang, Mordes, John P., Blankenhorn, Elizabeth P., Kashmiri, Himala, Kaldunski, Mary L., Jia, Shuang, Geoffrey, Rhonda, Wang, Xujing, Hessner, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027975/
https://www.ncbi.nlm.nih.gov/pubmed/23739610
http://dx.doi.org/10.1038/gene.2013.31