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Extraordinary response to crizotinib in a woman with squamous cell lung cancer after two courses of failed chemotherapy
BACKGROUND: The discovery of the fusion gene echinodermmicro tubule associated proteinlike 4-anaplastic lymphoma kinase, EML4-ALK, in patients with non-small-cell lung cancer has led to the remarkable development of anaplastic lymphoma kinase inhibitors, such as crizotinib. Consequently, the clinica...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027997/ https://www.ncbi.nlm.nih.gov/pubmed/24885608 http://dx.doi.org/10.1186/1471-2466-14-83 |