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Extraordinary response to crizotinib in a woman with squamous cell lung cancer after two courses of failed chemotherapy

BACKGROUND: The discovery of the fusion gene echinodermmicro tubule associated proteinlike 4-anaplastic lymphoma kinase, EML4-ALK, in patients with non-small-cell lung cancer has led to the remarkable development of anaplastic lymphoma kinase inhibitors, such as crizotinib. Consequently, the clinica...

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Detalles Bibliográficos
Autores principales: Wang, Qiushi, He, Yong, Yang, Xin, Wang, Yubo, Xiao, Hualiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027997/
https://www.ncbi.nlm.nih.gov/pubmed/24885608
http://dx.doi.org/10.1186/1471-2466-14-83

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