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Frequency of acute myeloid leukaemia-associated mouse chromosome 2 deletions in X-ray exposed immature haematopoietic progenitors and stem cells()

Exposure to ionising radiation can lead to an increased risk of cancer, particularly leukaemia. In radiation-induced acute myeloid leukaemia (rAML), a partial hemizygous deletion of mouse chromosome 2 is a common feature in several susceptible strains. The deletion is an early event detectable 24 h...

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Detalles Bibliográficos
Autores principales: Olme, C.-H., Brown, N., Finnon, R., Bouffler, S.D., Badie, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028086/
https://www.ncbi.nlm.nih.gov/pubmed/23665297
http://dx.doi.org/10.1016/j.mrgentox.2013.04.018