Cargando…

Synergistic effects of combined platelet-activating factor receptor and epidermal growth factor receptor targeting in ovarian cancer cells

BACKGROUND: Genetic alterations, including the overexpression of epidermal growth factor receptor (EGFR), play a crucial role in ovarian carcinogenesis. To date, EGFR targeting has shown limited antitumor effects in ovarian cancer when administered as monotherapy. We previously identified platelet-a...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Yi, Zhang, Mingxing, Zhang, Xiaoyan, Cai, Qingqing, Hong, Shanshan, Jiang, Wei, Xu, Congjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028110/
https://www.ncbi.nlm.nih.gov/pubmed/24886678
http://dx.doi.org/10.1186/1756-8722-7-39