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Hippocampal interneuron transplants reverse aberrant dopamine system function and behavior in a rodent model of schizophrenia

Schizophrenia patients exhibit increased hippocampal activity that is correlated with positive symptoms. While the cause of this hippocampal hyperactivity has not been demonstrated, it likely involves a decrease in GABAergic signaling. Thus, we posit that restoring GABAergic function may provide a n...

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Detalles Bibliográficos
Autores principales: Perez, Stephanie M., Lodge, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028118/
https://www.ncbi.nlm.nih.gov/pubmed/23979606
http://dx.doi.org/10.1038/mp.2013.111