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Dynamic Rearrangement of F-Actin Is Required to Maintain the Antitumor Effect of Trichostatin A

Actin plays a role in various processes in eukaryotic cells, including cell growth and death. We investigated whether the antitumor effect of trichostatin A (TSA) is associated with the dynamic rearrangement of F-actin. TSA is an antitumor drug that induces hyper-acetylation of histones by inhibitin...

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Detalles Bibliográficos
Autores principales: Yang, Dong-Hee, Lee, Jae-Wook, Lee, Jiyoung, Moon, Eun-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028200/
https://www.ncbi.nlm.nih.gov/pubmed/24846135
http://dx.doi.org/10.1371/journal.pone.0097352